Introduction
What is grit?
grit is a Scientific Data Management System (SDMS) designed for preclinical drug discovery.
It provides structured storage for experimental data—including, but not limited to, results from in vitro, in vivo, DMPK, and toxicology studies—alongside metadata for therapeutic modalities such as small molecules, oligonucleotides, and antibodies.
grit enables the creation and management of high-quality datasets with configurable metadata through intuitive forms and a robust import process. It features full ontology support and strict data validation. Administrators define the data structure, allowing scientists and data managers to enter information quickly and confidently, ensuring consistency and interoperability.
Therapeutic modalities
grit enables registration of a wide range of therapeutics modalities, referred to as Compounds, and optionally Batches in a single place. Define Compound Types and Compound Properties, and start registering small molecules (including structures), oligonucleotides, or anything you research with simple forms and a strictly validated data upload process. Information about registered modalities is easy to find with filtering and sorting.
Learn more about grit Compound and Batch registration
Experimental data
grit makes managing structured experimental data a breeze. Assay Types enable grouping data sets in broad categories, Assay Models define the shape of your experimental data and associated metadata, Assays provide an umbrella for directly comparable data sets and Experiments store your results. Results can be entered manually with simple forms and in bulk via a strictly validated data upload process. Results can be visualised in plots.
Ontologies
grit fully supports Ontologies for high quality, consistent and interoperable data. Vocabularies provide lists of controlled terms that can be used as data source for Compound Properties and data points in Experiments.
Learn more about grit Vocabularies
Security and user management
grit features Role-Based Access Control and optional two-factor authentication. Data is stored securely and accessible only by authorized users.
Learn more about security and user management
Basic functionalities
grit provides unified experiences for viewing tabular data with filtering and sorting, importing data in bulk, and exporting data.